CUSTOM ITEM: Guard Column cartridges, Bidentate C8, replacement, 4.0 mm ID x 10 mm long cartridges packed with 5 um, 300 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40008‑PG5‑3 Cogent Bidentate C8 Guard Column Cartridges are replacement cartridges designed to protect standard‑flow analytical HPLC columns when performing wide‑pore (300 Å) separations, especially for biomolecules and larger analytes.
Each cartridge is:
4.0 mm ID × 10 mm length
Packed with 5 µm, 300 Å TYPE‑C™ silica hydride Bidentate C8 phase
Constructed in stainless steel housings with SS frits
Cartridges are individually packaged in protective Delrin™ cases, preventing contamination, drying, or damage before use.
⚠️ Requires guard column holder (sold separately)
Designed for Standard Analytical Column IDs
These cartridges are optimized for:
3.0 mm ID solvent‑saving columns
4.0 mm ID analytical columns
4.6 mm ID standard HPLC columns
Ideal for conventional HPLC systems, offering:
Minimal band broadening
Maintained efficiency and resolution
Consistent chromatographic performance
Why Use 300 Å Guard Cartridges
The 300 Å pore size is specifically designed for:
Peptides and proteins
Large molecular weight analytes
Complex biological samples
Compared to 100 Å phases, 300 Å:
Improves accessibility for large molecules
Reduces steric hindrance
Enhances recovery and reproducibility for biomolecule separations
Why Use Replacement Guard Cartridges
Analytical columns are exposed to:
Particulates and debris
Strongly retained compounds
Matrix buildup from complex samples
Irreversible adsorption
The 40008‑PG5‑3 cartridges provide a sacrificial protection layer, helping to:
Extend analytical column lifetime
Maintain consistent chromatographic performance
Reduce downtime and replacement costs
Improve reproducibility across runs
Cartridges can be replaced quickly without disturbing the analytical column.
Bidentate C8 Guard Phase Advantages
Using the same stationary phase as your column ensures:
Matched selectivity and retention behavior
No method disruption
Seamless analyte transfer
Compared to C18:
Reduces excessive retention
Improves recovery of amine‑containing compounds
Provides alternative selectivity for complex matrices
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Reduced silanol activity
Improved peak shape for basic and polar analytes
Lower secondary interactions
Faster Equilibration
Reduced cycle time
Increased throughput
Durability
Resistant to hydrolysis
Long cartridge life
Stable under routine and demanding conditions
Typical Applications
LC‑MS and HPLC biomolecule analysis
Peptides and protein separations
Pharmaceutical and bioanalytical workflows
Complex biological matrices
Wide‑pore analytical chromatography
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable